Ibuprofen for Pain Relief

Relieving discomfort is actually half the battle

I flinch every time the memory of one of my countless urinary tract infections (UTIs) hits me like a bolt of lightning. The pain when using the toilet is truly nasty, and the smouldering background pain in between feels like torture. I wouldn't wish a UTI on my worst enemy!

Looking back, I focused far too little on pain management. I usually just pushed through, sometimes for shorter periods, sometimes longer.

This probably stems from one of my ingrained beliefs, like: If it’s not absolutely necessary, then no medication. But sometimes it's just smarter to push past that and free yourself from the agony.

Do you suffer from recurring UTIs, and even in between (when no infection is detectable), are you plagued by a nagging feeling or even a slight, hard-to-describe pain in your bladder? It might help to "break through" this perceived pain/phantom pain with spasmolytics (e.g. Buscopan®*). I can still vividly remember my time with recurring UTIs. It was as if the pain had "burned in", because I literally no longer knew what a happy bladder felt like.

Cystitis: Ibuprofen for Pain

Good to know

Medical guidelines of the highest quality level acknowledge the importance of symptomatic therapy for mild to moderate symptoms and recommends Ibuprofen, phytopharmaceuticals (herbal medicines), and D-Mannose beyond the use of antibiotics.

The background for this recommendation is a study that compares a three-day therapy with Ibuprofen (3 x 400 mg) with the immediate single-dose administration of Fosfomycin. The non-steroidal Ibuprofen performs only slightly worse. With Ibuprofen, 70% of women were symptom-free after a week, compared to 80% with the antibiotic.

A genuine alternative to antibiotics and at the same time a pragmatic approach, considering the increasing development of bacterial resistance.

Quick Overview

  • Ibuprofen*: A classic with 400 mg Ibuprofen
  • Buscopan®*, Spasuret®*: Spasmolytics reduce the increased tone of the overactive bladder muscle. A double-edged sword, as it also brings bladder emptying disorders and several other contraindications.
  • Sodium bicarbonate*, Alkaline tablets*: If you don't want to use chemical painkillers, alkaline urine can reduce bladder burning. Dosage as needed until relief occurs.
    WARNING: Do not take too much sodium bicarbonate as it can cause significant side effects/poisoning.
  • Acupressure mat*: Dulls the pain in the bladder and simultaneously strengthens the bladder meridian. Simply stand on the spiky mat and slowly step in place (if you can handle it).
  • Relaxation techniques: Try everything to counteract the tension. Lie down, breathe deeply into your belly, and listen to guided pain-relief meditation.

FAQ

Painkillers for Cystitis

Painkillers can definitely alleviate your suffering from cystitis. A medical guideline recommends Ibuprofen because it also has anti-inflammatory properties. Read more...

Non-steroidal anti-inflammatory drugs (NSAIDs), such as Ibuprofen and Diclofenac, are analgesic, antipyretic, and anti-inflammatory.

Also effective but prescription-only is Metamizole (Novaminsulfon®, Novalgin®).

Paracetamol is analgesic and antipyretic but has no anti-inflammatory effect.

For cramp-like bladder pains, antispasmodics (Buscopan®, Spasuret®) help.

For overactive bladder, prescription anticholinergics (Spasmex®) are also used.

Read more...

Without chemicals, things like warmth & relaxation, baking soda* for burning, and an acupressure mat can help. Read more...

It all depends on the dosage, form of administration, individual susceptibility, and the type of pain.

For cramp-like pains, there are antispasmodics like Buscopan®*; for general pain, milder painkillers like Ibuprofen or Metamizole (Novalgin®) are recommended.

However, not everyone responds equally well to the same painkiller. Read more...

Warmth, rest & relaxation, anti-inflammatory painkillers like Ibuprofen or Metamizole (Novalgin®), and antispasmodic painkillers like Buscopan® PLUS or Spasuret®*. Read more...

Warmth and painkillers like Ibuprofen or Metamizole (Novalgin®), antispasmodic painkillers like Buscopan® PLUS or Spasuret®*.

Dosage tip: 1 tablet of Ibuprofen with 400 mg doesn't noticeably help me with bladder pain. Therefore, I take the maximum single dose of 2 tablets of 400mg each. Read more...

The combination of antibiotics and painkillers can lead to unwanted interactions. Do not take fluoroquinolones (all substances ending in -floxacin, e.g. Ciprofloxacin) together with anti-inflammatory drugs (Diclofenac or Ibuprofen). Read more...

Opioid analgesics (Tramadol, Tilidine, Morphine, Oxycodone, etc.) are substances with a morphine-like effect. However, due to a multitude of undesirable side effects, I cannot recommend these drugs for cystitis. Read more...

Very strong painkillers from the category of opioid analgesics. Read more...

Antispasmodic painkillers. Spasmolytics are often used as "bladder-calming" medications for an overactive bladder ("irritable bladder", "urge bladder"). Read more...

The topic of "overactive bladder" alone could fill entire books. Since the main focus of my website is on cystitis, I don't want to go into too much detail here.

Behavioural changes, bladder training, pelvic floor exercises, bladder-regulating medications, etc. Read more...

Spasmolytics calm the bladder and relieve the overactive urge to empty the bladder - but not without side effects. Therefore, when taking anticholinergics, there are a few things you should know. Read more...

Ibuprofen relieves pain and reduces inflammation. According to a study, the use of Ibuprofen and antibiotics is quite comparable.

For otherwise healthy women with mild to moderate symptoms, symptomatic treatment with anti-inflammatory painkillers is often sufficient. Read more ...

Paracetamol is available over-the-counter and popular, but unlike NSAIDs (such as Ibuprofen and Diclofenac), it does not have an anti-inflammatory effect. Since the bladder wall is inflamed during an acute bladder infection, NSAIDs have a beneficial double effect. Read more ...

Phenazopyridine is a urinary analgesic and relieves burning, urgency, frequency, and pain associated with bladder issues. Available as: Azo Standard, Pyridium, Prodium, Pyridiate, Baridium, Uricalm, Urodine, UTI Relief. Read more ...

If tolerated, the anti-inflammatory Ibuprofen is preferred. Read more ...

NSAIDs like Ibuprofen have a significantly anti-inflammatory effect, while Metamizole (e.g. Novalgin®) and Paracetamol do not have a notable anti-inflammatory effect.

For a bladder infection, a painkiller like Ibuprofen also has the positive side effect of reducing inflammation. However, there are specific indications for the prescription-only Metamizole. Read more ...

Metamizole is a prescription pain reliever with a weak anti-inflammatory effect. It causes fewer gastrointestinal side effects than NSAIDs like Ibuprofen and is often prescribed for kidney insufficiency. Read more ...

Buscopan® belongs to the group of anticholinergic antispasmodics and is used, among other things, for spasmodic pain in the urinary tract.

Buscopan PLUS® combines this with the pain-relieving property of Paracetamol. User opinions are mixed. For some, it is the remedy of choice, while others report little noticeable relief from the painful symptoms. Read more ...

The maximum single dose for adults should be no more than 800 mg Ibuprofen (= 2 tablets 400 mg IBU-ratiopharm®).

Within 24 hours, do not exceed 2400 mg Ibuprofen (= 6 tablets 400 mg IBU-ratiopharm®). Read more ...

An antibacterial effect has only been demonstrated in in vitro studies so far. However, there are other reasons why NSAIDs like Ibuprofen can be helpful for a urinary tract infection: they relieve pain and reduce inflammation. Read more ...

A study compared treatment with Ibuprofen versus the antibiotic Fosfomycin. The conclusion: More than half were symptom-free without antibiotics.

Whether you are among those who can be successfully and complication-free treated without antibiotics is always unclear beforehand.

For me, this means that I use Ibuprofen as a painkiller and anti-inflammatory. If there is no improvement in combination with herbal remedies after about 3 days, => off to the doctor’s to arrange a urine culture and, depending on the result, possibly antibiotics. Read more ...

In the last trimester of pregnancy, most painkillers (except Paracetamol) are contraindicated.

Information from the package inserts:

  • Paracetamol is okay throughout pregnancy
  • Ibuprofen only in the first and second trimesters (up to 27 weeks of pregnancy)
  • Acetylsalicylic acid (e.g. Aspirin®) only in the first 12 weeks of pregnancy
  • Metamizole (e.g. Novalgin®) only in the first and second trimesters (up to 27 weeks of pregnancy)

The beloved Paracetamol is, however, controversially discussed in an article from the Kiel Pain Clinic. Read more ...